THE PURPOSE OF THIS STUDY:
To determine if a portion of outdoor air pollution, diesel exhaust and
nitrogen dioxide, directly causes irritation or inflammation in the lungs,
according to cells and biochemical substances (mediators) in the sputum.
We also believe that certain enzymes in the lungs affect the severity of
the inflammation and are produced according to our genes (material
passed from parent to child that determines the make-up of the body and
mind). Results from this study may increase the understanding of how air
pollution can affect the function of the lungs and body, in particular, in
people with allergic asthma.
Screening Visit:
Brief study visit which take about 4 hours. During this time you will
receive, allergy skin test (8 allergens on forearm a physical examination,
breathing test, heart tracing (ECG) and exercise test.
Exposure Sessions:
Once you are accepted into the study you will be required to be at the
laboratory from 7:30 am ~ 12 noon on each of the 3 exposure days. Each
exposure is 1 month apart. At each session you will have complete tests
(ECG, Pulmonary tests, & Various other test). One exposure is diesel
exhaust (no worse then sitting in traffic for 2 hours) while exercising on a
stationary bike in a special room (chamber) for 15 minutes every 30
minutes for 2 hours. The other 2 exposures will be clean filtered air and
nitrogen dioxide.
Day 2 ~ following day after Exposure Session:
You will be at the laboratory from 9am ~ 1100 for follow up tests (ECG,
Pulmonary tests, & other tests
To determine if a portion of outdoor air pollution, diesel exhaust and
nitrogen dioxide, directly causes irritation or inflammation in the lungs,
according to cells and biochemical substances (mediators) in the sputum.
We also believe that certain enzymes in the lungs affect the severity of
the inflammation and are produced according to our genes (material
passed from parent to child that determines the make-up of the body and
mind). Results from this study may increase the understanding of how air
pollution can affect the function of the lungs and body, in particular, in
people with allergic asthma.
Screening Visit:
Brief study visit which take about 4 hours. During this time you will
receive, allergy skin test (8 allergens on forearm a physical examination,
breathing test, heart tracing (ECG) and exercise test.
Exposure Sessions:
Once you are accepted into the study you will be required to be at the
laboratory from 7:30 am ~ 12 noon on each of the 3 exposure days. Each
exposure is 1 month apart. At each session you will have complete tests
(ECG, Pulmonary tests, & Various other test). One exposure is diesel
exhaust (no worse then sitting in traffic for 2 hours) while exercising on a
stationary bike in a special room (chamber) for 15 minutes every 30
minutes for 2 hours. The other 2 exposures will be clean filtered air and
nitrogen dioxide.
Day 2 ~ following day after Exposure Session:
You will be at the laboratory from 9am ~ 1100 for follow up tests (ECG,
Pulmonary tests, & other tests
To participate in the Asthma study you must be:
 | 18 - 55 years old | |
| In good health (other then asthma) | |
| Non-Smoker | |
| Total of 8 visits over approximately 3 months at our laboratory | |
| Visits are conducted Monday ~ Friday, 7:30am start time. | |
| Compensation of up to $700.00 upon completion of study | |
Asthma & Cat Sensitive Asthmatic Studies
562 401 7563
| Environmental Health Services of Los Amigos Research and Education Institute, Inc. |
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To participate in the CAT sensitive Asthma study you must be:
| 18 - 55 years old | |
| In good health (other then asthma) | |
| A positive reaction to CAT skin test | |
| Cannot be exposed to CATS during study | |
| Non-Smoker | |
| Total of 10 visits over approximately 3 months at our laboratory | |
| Visits are conducted Monday ~ Friday, 7:30am start time. | |
| Compensation of up to $800.00 upon completion of study | |